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Key Information



Ultram (Tramadol)


cyclohexanol hydrochloride

Tramal, Ultram


Tramadol is an opiate. Although it is weaker than heroin and methadone, it still causes all the typical opiate effects, alongside some effects due to increases in serotonin activity. The effects include:  Feelings of warmth and well-being, relaxation and sleepiness.   Typical opiate effects of fatigue, drowsiness, nausea and retching, constipation and sometimes confusion.  Less often, diarrhoea, dizziness or fainting, excessive sweating, itching, raised blood pressure, tightness in the airways, muscle weakness, sensory disturbances, hallucinations, fits and blood disorders.    


Tramadol comes in tablet form and is taken orally.

HEALTH RISKS (long term) which includes withdrawal & tolerance:

Although tramadol is not as potent as the strongest opiates like heroin, it still acts as an opiate, and also has additional risks due to its actions on serotonin levels.  If you have epilepsy or are taking certain antidepressants you should definitely only take tramadol with clear medical advice because of the known risks.  Tramadol can depress breathing and may be risky in asthma and chronic obstructive pulmonary disease.  Tramadol use has been linked with ‘serotonin syndrome’. This is a potentially life threatening condition where the serotonin receptors are over stimulated, which can lead to high fever, rapid pulse, shivering, sweating, trembling, muscle twitches and agitation and confusion.  Pregnant women should not use tramadol as it can be toxic to the developing foetus.  Tramadol is a drug used to treat severe pain, but it is habit forming.


Tramadol is not controlled under the Misuse of Drugs Act, but is only available with a prescription from a doctor or other healthcare professional that is qualified to prescribe.  It is illegal for anyone else to supply it.

  1. Tramadol belongs to the class of drugs known as opiate agonists. Primarily, Tramadol works by changing the way the body senses pain.
  2. Tramadol, when combined with certain other substances, can increase central nervous system and respiratory depression.
  3. Tramadol  was invented by the pharmaceutical company Gruenenthal GmbH, located in Stollberg, Germany, in late 1970s.
  4. Seizures (convulsions) have occurred in some people taking this medicine.
  5. As a narcotic-like drug, Tramadol  has significant potential for abuse. People should never inhale crushed tablets or dissolve the tablets and inject them into the body. These actions can be fatal.
  6. Tramadol may impair mental ability and physical coordination. Alcohol may intensify these effects and increase the risk of accidental injury. People taking Tramadol are cautioned to avoid alcohol.
  7. Tramadol is an opioid that is chemically related to codeine and is used to treat mild to moderate pain.
  8. Tramadol the most recommend pain relief drug by doctors.
  9. Tramadol may be expected to have additive effects when used in conjunction with alcohol, other opioids or illicit drugs that cause central nervous system depression. Serious potential consequences of overdosage with tramadol are central nervous system depression, respiratory depression and death. Tramadol has mu-opioid agonist activity, can be abused and may be subject to criminal diversion.
  10. Tramadol is a centrally acting analgesic agent which has a weak opiate agonist action but also inhibits norepinephrine reuptake and stimulates the release of serotonin.
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